Welcome to dbEBV

As one of the nine known human herpesvirus types, the Epstein–Barr virus (EBV, formally called human gammaherpesvirus 4)was discovered in 1964 and is one of the most common viruses in humans. EBV is associated with various cancers and diseases, such as infectious mononucleosis, lymphoma, gastric cancer, nasopharyngeal carcinoma and so on. Since the first EBV genome sequence, B95-8, was published in 1984, massive EBV genomes have been sequenced and published, and the relationship between EBV variants and the risk of diseases/cancers have attracted great attentions.

Here, we presented the dbEBV (the database of Epstein-Barr Virus) database, which hosted the curated 942 EBV genomes with 109,893 variant loci from different tissues or cell lines in 24 countries. The details about the genomes including EBV type, sample type, phenotype and NPC incidence were integrated. Furthermore, the evolutionary trees based on entire genomes or individual genes have been constructed and interactively visualized. Various search and browse options were provided in the database for convenient queries.